I remember the first virus, a "Blackjack" variety, pretty nasty, perhaps an "archetype" of others that followed, was on a 5 1/4" factory shipped disk from the Rolleimetric factory in Braunschweig, Germany where the German Federal Bureau of Aircraft Accidents Investigation is located, by way of Prometric Technologies in Canada, 1990. A close-range photogrammetry system, then on Intel 386/387 CPUs, uses a "documented" camera and lens and software to bring aerial mapping metrology to earth, so to speak, for the close measurement of a number of scenarios, i.e., aircraft and car crashes, the native American leader, "Crazy Horse" sculpture, geologically unstable formations, "as-built" buildings, etc., either from the ground or helicopter. The small firm, Grossman and Associates, I worked in, he a writer of the yearly Encyclopedia Britannica entry on archaeology in the Western Hemisphere, used it to record a number of sites, for example, the archaeology of Mead Hall at Drew University, the recovered US Civil War R.P. Parrott rifled cannon gun-platform ("Swamp Angel") and the "workers houses" both at the historic "West Point Foundry" in an EPA ordered remediation of the Marathon Battery National Priority Site in Cold Spring NY. Today, many of those online info services he queried have been replaced by the proverbial "Ariel" in Shakespeare's "The Tempest" who would span the distance of the world in seconds, the Internet.
I use the German Avira AntiVir software but I have had since 1983, a fair share of problems some I'm not sure if it would take a forensic analysis of why the disks crashed and locked, suspected CMOS viri, perhaps (Wikipedia "CMOS" entry).
Newsvine - 10 Worst Computer Viruses of All Time